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Safira eClinical Consulting

We offer valuable support and guidance to help Sponsor Clinical Research teams make good decisions to select the best technology and enhance their clinical trial processes.

Read our latest UAT blog post on User Acceptance Testing.

Let us start with the conclusion:

The Sponsor is ultimately responsible for User Acceptance Testing (UAT) of the final system and should do conduct an independent UAT.

There seems to be some confusion about what UAT is in the context of the configuration of an eCOA solution for a clinical trial.

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Developing a Robust Data Monitoring Plan

Data monitoring in clinical research begins with a strategic plan that outlines the entire data lifecycle—from collection and storage to analysis and reporting. This plan is crucial and should be established before the study commences to ensure clarity and consensus among all stakeholders. A comprehensive data monitoring plan not only sets the groundwork for how data will be handled but also defines the timelines and responsibilities, ensuring that every piece of data collected contributes meaningfully to the study’s objectives.

License Management in Clinical Trials

License management in clinical trials is crucial for ensuring the timely and compliant use of questionnaires and other licensed materials. Managing these licenses effectively prevents study delays, legal issues, and financial liabilities. As part of the preparatory phase, sponsors must secure appropriate licenses before patient enrollment begins, particularly when electronic implementations are involved.

Improve patient reported outcome data collection by streamlining documentation with proper eCOA training for researchers, site staff and patients.

eCOA, or electronic clinical outcome assessments, includes:

  • Patient-Reported Outcomes (PRO)
  • Clinician-Reported Outcomes (ClinRO)
  • Observer-Reported Outcomes (ObsRO)
  • Performance Outcomes (PerfO).

Implement Structured Change Management for Success

Change management is crucial in clinical trials to successfully adopt new technologies, processes, and procedures. The dynamic nature of clinical research demands constant adaptation to new findings, regulatory requirements, and technological advancements. Safira understands that while change is necessary, it can disrupt operations without a proper management plan. Our structured approach ensures that transitions are managed smoothly, minimizing impact and maximizing adaptation speed across your operations.

Improve patient reported outcome data collection by streamlining documentation with proper eCOA training for researchers, site staff and patients

eCOA, or electronic clinical outcome assessments, includes:

  • Patient-Reported Outcomes (PRO)
  • Clinician-Reported Outcomes (ClinRO)
  • Observer-Reported Outcomes (ObsRO)
  • Performance Outcomes (PerfO)

Recruiting Clinical Trial Participants Where They Are

Safira can help you leverage social media platforms as part of a greater strategy to improve efficiency, reduce time and budget and improve diversity for your trial recruiting initiatives.

 

Social Intelligence Report: Patients & Clinical Trials in the U.S. ebook

Safira’s Center for Social & Digital Excellence recently completed a social intelligence report looking at the trends in social conversations from patients and caregivers regarding their feelings and drivers related to clinical trials.

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Revolutionize your clinical research with eCOA

eCOA – the advanced electronic data collection system that streamlines trials, enhances patient compliance, and delivers high-quality, real-time data while ensuring patient privacy and regulatory compliance.

Enhanced Patient Understanding

Empower your clinical trials with eConsent – a streamlined, digital solution for informed consent that enhances patient understanding, boosts efficiency, and reduces administrative hassle, while ensuring regulatory compliance and accessibility for all.

Randomization & Trial Supply Management

Optimize your clinical trials with RTSM – a comprehensive system that streamlines participant randomization, treatment assignment, and trial supply management for a safe, efficient, and cost-effective research experience.

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Tuberculosis: Patient Sentiment

09th, October 2024 | Social Listening/Intelligence

We recently conducted a comprehensive, multilingual analysis of social media conversations regarding tuberculosis, focusing on insights from Japan, the Philippines, India, and Peru. Initially, we sifted through over 3 million posts from 1 million authors, but after narrowing our focus to consumer discussions, we analyzed 363,522 posts by 176,977 individuals from these countries, spanning from September 2022 to September 2024.


Globally, tuberculosis affects approximately 10.6 million people annually, including 5.8 million men, 3.5 million women, and 1.3 million children. Despite being both curable and preventable, tuberculosis remains pervasive worldwide, claiming about 1.3 million lives each year* and potentially infecting up to 2 billion people**.

Tuberculosis statistics


Our data collection leveraged advanced social intelligence software to capture multilingual, public digital and social media interactions from platforms like Facebook, Reddit, forums, blogs, video comments, and news sites. Initially examining 16 countries, we honed in on the four with the most robust public dialogue about tuberculosis. Even after adjusting for population differences, Japan and India emerged as leaders in conversation volume, followed by Peru and the Philippines.

global tuberculosis social conversation trends


Japan alone accounted for more than a third of all discussions, with over 130,000 posts. Sentiment analysis revealed a predominantly positive tone across these countries, though there was a noticeable contrast between the Asian nations—Japan, the Philippines, and India—and the South American country of Peru.

tuberculosis social conversation trends

The sentiment drivers varied by country:
Japan
Exhibited a high positive sentiment of 91.3%, possibly due to strong public trust in healthcare systems, effective public health campaigns, and recent advancements in TB management and treatment.

tuberculosis social conversation Japan

Peru
Displayed a lower positive sentiment at 48.9%, which may reflect mixed public reactions stemming from challenges in healthcare access, TB management, or public awareness efforts.

tuberculosis social conversation Peru


India: Showed 68% positive sentiment, driven by successful TB control programs and improvements in healthcare infrastructure, although significant negative sentiment persists due to ongoing challenges, particularly in rural areas.

tuberculosis social conversation India


Philippines
Had the highest positivity at 81.4%, likely reflecting effective public health strategies, community support, and the successful integration of TB services with other healthcare initiatives.

tuberculosis social conversation Philippines


Interestingly, our analysis noted a significant uptick in discussions from 2022 to 2023, with a slight decline in 2024, though still higher than in 2022. The conversation was notably prevalent among the youth, with the under-18 demographic over-indexing by 0.58% followed by the 18-24 age group at 0.51%, indicating that tuberculosis is a particularly salient issue among younger populations.

tuberculosis social conversation 2-year trend
tuberculosis social conversation trends age


In terms of gender distribution, males dominated the public discourse on tuberculosis, a rare occurrence as women typically are more vocal about health issues both personally and within their families. This unique finding underscores the broad and unique impact of tuberculosis across different demographics.

tuberculosis social conversation gender

Our extensive analysis of public conversations about tuberculosis in Japan, the Philippines, India, and Peru provides crucial insights into the global perception and sentiment surrounding this infectious disease. From September 2022 to September 2024, we captured a snapshot of how tuberculosis is discussed among the public through a focused review of 363,522 social media posts by 176,977 individuals. Despite tuberculosis being a preventable and curable disease that affects over 10.6 million people worldwide, our findings suggest a robust dialogue with varied sentiments across different regions.

Japan led the discussions with over 130,000 posts, reflecting a highly positive sentiment (91.3%), likely due to strong public health initiatives and trust in the healthcare system. Conversely, Peru showed a more mixed response with a 48.9% positivity rate, possibly indicating issues in healthcare access or public health strategy effectiveness. India and the Philippines also showed significant engagement with the topic, with sentiments of 68% and 81.4% positive respectively, pointing to active public health communications and community engagement efforts.

Our study highlights the importance of continuous social intelligence monitoring to gauge public awareness and attitudes toward health issues like tuberculosis. This approach not only helps in understanding public sentiment across different cultural contexts but also aids in tailoring public health responses to enhance engagement and effectiveness of health communication strategies. By tracking these conversations over time, stakeholders can better address the gaps in public health strategies and improve the overall response to tuberculosis globally.

To learn more about Safira’s Social Intelligence services visit our Social Intelligence Services page where you will learn how social intelligence can support clinical trial site recruitment, facilitate more effective site choices, understand the challenges, barriers, needs and language of the patients you’re hoping to recruit for your study. Social intelligence can also provide multilingual, global and real time analysis of conferences, industry trends, brand and product sentiment among professionals and consumers, symptoms and side effects of disease, and preferred treatment. Click Here to contact us or learn more.

*World Health Organization 7 November 2023
**Centers for Disease Control TB Overview Fact Sheet 2024

Michael Durwin

A pioneer in social media marketing, Michael has supported brands across numerous industries including Disney, Germany Tourism, Subaru, Xfinity, Coca-Cola, the United States Army, and many others, in social media efforts for 28 years.
Social Intelligence Report: Patients & Clinical Trials in the U.S.

Social Intelligence Report: Patients & Clinical Trials in the U.S.

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